01The direction of the switch is the whole memo
People memorize 'two weeks for MAOIs' and apply it both ways. That shortcut injures the Prozac-to-MAOI direction.
Parent half-life after chronic use is about four to six days. Norfluoxetine can run four to sixteen days. Plasma still argues with you after the last 10 mg capsule.
Linezolid and IV methylene blue sit in the same syndrome chapter. Tell a ward about yesterday's Prozac even if it was 'only 10.'
02Fourteen days one way, five weeks the other
MAOI stopped, then Prozac: wait at least fourteen days.
Prozac stopped, then MAOI: wait at least five weeks. Longer if the course was chronic or high-dose, the insert allows that hedge.
A 10 mg file that lasted a year is still a long-tail file. Do not bargain with day counts on a forum.
| From | To | Label gap |
|---|---|---|
| Psychiatric MAOI | Prozac | ≥14 days |
| Prozac | Psychiatric MAOI | ≥5 weeks |
| Prozac | Linezolid / IV methylene blue | Do not start on them |
03Why the Uxora 10 mg lock does not help you cheat the calendar
Lower milligrams still produce norfluoxetine. The washout is about half-lives, not about a SERP lock looking small.
Missed capsules do not reset the five-week clock to zero in a helpful way. The metabolite is already there.
04What to say when a new team has twelve minutes
Last Prozac date. Milligrams. Other serotonergic drugs. If they say 'we always wait two weeks,' show the five-week sentence.
Mail [email protected] if our docket ever writes fourteen days both ways. That would be a bug.
Washout pocket lines
- 5 weeks Prozac → MAOI
- 14 days MAOI → Prozac
- 10 mg does not shorten
- Tell wards about linezolid
05Other serotonergic swaps that are not this memo
Switching between SSRIs is a psychiatrist's taper, not a five-week law every time. Do not apply MAOI math to every antidepressant change.
Adding modafinil is a CYP story, not an MAOI story. Different memo. Different risk.
Activation in week one is the other chip. Do not call jitter a washout.
06A twelve-minute ward script when someone says 'we always wait two weeks'
Hand them three facts. Last Prozac date. Milligrams, even if 10. Direction of the planned MAOI. Then the sentence: after fluoxetine the labeled gap to a psychiatric MAOI is five weeks, not fourteen days. Fourteen days is the other arrow.
If they say the patient 'feels clear' at day twelve, answer that feeling clear is not a norfluoxetine assay. Parent half-life after chronic use is about four to six days. The metabolite can run four to sixteen. A year-long 10 mg file is still a long-tail file.
Linezolid and IV methylene blue belong in the same breath. A pneumonia team that wants linezolid tonight needs yesterday's Prozac on the list, not hidden because it was a small capsule.
Do not apply five-week math to every SSRI-to-SSRI change. That is a psychiatrist's taper, not an MAOI law. Do not apply fourteen days both ways. That is the error this memo exists to kill.
Weekly 90 mg in the past still counts as fluoxetine exposure. Do not average strengths into a shorter wait.
Herbal 'instead of an MAOI' is not a shorter wait. Serotonergic herbals can still pile. Ask. Do not stack St John's wort into a washout as a clever shortcut.
Activation in week one is not washout. Keep that on the activation chip.
If syndrome signs are already in the room - rigidity, fever, autonomic swings, delirium - this memo is over. Emergency care. Portugal: 112.
Mail [email protected] if any Uxora page writes fourteen days after Prozac toward an MAOI. That is a bug.
07Keep the long arrow on the chart
Washout is directional. The full SSRI file is the fluoxetine docket.
Disclaimer still applies. Sofia does not time your MAOI from Cedofeita.
Write the two arrows on the chart in ink. MAOI then Prozac: fourteen days. Prozac then MAOI: five weeks. Mixing them is the error that keeps reaching this desk.
A 10 mg file that lasted a year still leaves norfluoxetine. Bargaining with day counts because the lock looks small is how day-eight phenelzine plans get written.
Feeling clear at day twelve is not an assay. The metabolite does not email when it leaves. Keep the five-week rule.
Linezolid tonight plus Prozac yesterday is a ward sentence, not a hidden 10 mg. ID and psychiatry share the hold.
IV methylene blue sits in the same chapter. A surgical team needs the last capsule date on the list.
Weekly 90 mg in the past still counts as fluoxetine exposure. Do not average 90 and 10 into a shorter wait.
SSRI-to-SSRI changes are a psychiatrist's taper. Do not glue five-week MAOI math onto every antidepressant swap.
St John's wort is not a shorter MAOI. Do not stack a herbal serotonergic into a washout as a clever gap-filler.
Activation in week one is the other chip. Jitter is not washout and washout is not jitter.
Modafinil on the same chart is a CYP pair, not an MAOI pair. Different memo. Different risk.
If rigidity, fever, and autonomic swings are already in the room, stop reading. Emergency care. 112.
Chronic high-dose language on the insert allows a longer-than-five-weeks hedge. This desk will not shorten. Specialists can lengthen.
Mail the desk if any Uxora page writes fourteen days after Prozac toward an MAOI. That is a bug.
Sofia will not start your MAOI from Cedofeita. She will keep the arrows pointed the right way.
Fourteen days and five weeks are different arrows. Do not invert them.
Day-ten comfort is not an assay. Five weeks still sits on the MAOI-after-fluoxetine file.
Methylene blue is a surgical warning. A week off 10 mg is not five weeks.
Linezolid is not a leftover UTI fix next to fluoxetine.
A homemade 5 mg taper does not shorten the labeled washout.
St John's wort is another serotonergic. It does not belong in a washout.
A sertraline cross-taper is not this memo's job. MAOI clocks are.
Travel does not write an early MAOI start.
Norfluoxetine can linger for weeks. That is why the long clock exists.
This memo will not quote a dollar for a washout. Time is the lock.
Sofia Mendes will not countersign a day-ten MAOI start from an email.
Keep the last 10 mg date on a card. Surgeons and new psychiatrists both need it.
Fourteen days and five weeks are different arrows. Write the last 10 mg date on a card. Surgeons, new psychiatrists, and travel clinicians all need that date.
Methylene blue and linezolid carry MAOI-like warnings. A week off 10 mg is not five weeks. Tell the surgical and UTI desks the real date.
A homemade 5 mg sprinkle does not shorten washout. Clocks start from the last dose the owner recognizes.
St John's wort is another serotonergic. It does not belong in a washout tea.
A sertraline cross-taper is a named-owner file. This memo only stamps the MAOI clocks. Two weeks is not a universal green light.
Travel at week four does not write an early MAOI start. Pack the date, not a forbidden first tablet.
Feeling well is not a plasma assay. This desk will not invent a monitored exception from a comment.
This memo will not quote a dollar. Time is the lock. Prozac 10 mg is the strength this site stamps.
Sofia Mendes will not countersign a day-ten MAOI start from [email protected].
Keep the 10 mg bottle until the washout talk is done so the last date is not a guess.
Write the last 10 mg date on a card and keep the bottle until the washout talk is done. Surgeons and new psychiatrists both need that date, not a guess.
Five weeks after fluoxetine is the MAOI-after arrow. Fourteen days is the other arrow. Do not invert them because you feel well at day ten.
A homemade 5 mg sprinkle does not shorten the clock. St John's wort does not belong in the quiet period.
Travel at week four does not write an early MAOI start. Pack the date. Leave the forbidden first tablet at home.
This memo will not quote a dollar. Time is the lock. Sofia Mendes will not countersign a day-ten start from email.
Prescribed-online still means a licensed clinician where you live. This inbox cannot become a monitored exception.
Norfluoxetine can linger for weeks. That is why the long clock exists after the last 10 mg. Feeling well at day ten is not an assay. Keep the last-dose card with the bottle.
A sertraline cross-taper is a named-owner file. This washout memo only stamps the MAOI arrows. Fourteen days one way. About five weeks the other. Do not invert them for travel.
This Porto file will not invent a monitored exception from a comment. Sofia Mendes peer-passes the clocks. She does not start an MAOI from [email protected].
Keep the last 10 mg date on paper, not in a thread. Methylene blue and linezolid still need that date. This washout memo will not invent a gap and will not quote a dollar.
Sources
- Prozac PI 2.9 / 4.1: 14 days after MAOI; 5 weeks after Prozac before MAOI.
- PK: norfluoxetine t½ up to ~16 days; parent 4-6 days chronic.
Checked against the current label and reviewed by Dr. Sofia Mendes. See Intake, Markup, Peer-pass, File.